[Page 1]

After I wrot you last Sir Dunlop
tried the Injections mentioned by Dr. Campbell
for some days but although they suspended the
Downward press which distress him always for
several hours after taking the injection he
discontinued the use of them from finding
they brought on such a degree of costiveness
as was not to lie get the better of by this Laxi¬
tives that used to operate on his constitution
and when he added to the doze its effects proved
so violent as to be distressing at the time from the
pain in the Bowels and even limbs it occasiond
and exhausting afterward from a continued eva¬
cuation of some days

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[Page 2]

In addition to this uneasie state he has been often
troubled with toothachs and Cramps in his limbs his
appetite is much declined and he loses flesh while
the original Complaint remains much in the same
train as ever yet as when free of the toothach and
that Nausea common to a weak appetite he has no
disturbing pain and does not flatter himself with
a recovery nor greatly fear the end alloted to
all our complaints he is unwilling to try any
medicines that might give a more painfull turn
to his distemper and make Life vexatious in
trying to promote its duration what he would
therefore request of your Skill is some prescription
that might tend to keep him more regular in his
Belly and prevent costiveness without risque of
inducing a contrary extreme if you can send him
any preparation from which you expect this effect
it you are so good as apply to Mr William Kerr

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[Page 3]

Esqr. Surveyor of the general post office he is my
friend and with frank any little bose or bottle of
medicine for Sir Dunlop by post if put up in a
way that cannot injure the letters in the Bag for
Stewarton

I ought perhaps to have told you when the in¬
jections were used it was once a day their effect seemd
to continue Six or Seven hours before pressure
returned or the watery evacuation which then came
as usual the costiveness was at one time so obstinate
against medicine for four days and then the distention
and strain so violent that quite alarmed by it I ven¬
tured to prescribe an injection of Chicken broth as
an aleviating relief but since I have sometimes been
thinking if instead of once a day it might not have been
proper to have exhibit this astringent medicine oftner
about the period of its visible effect with now and
then as once in one or perhaps two days an emolient
injection between but this I only submit to your consi¬

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[Page 4]

deration as Sir Campbell was not at all particular
in his directions and wished only to move in Obedience
to your Ideas and Superior judgment only I must again
remind you that in giving your advice no uncertain
expectation would be an equivalent for the risque
of bringing on any very painful or distressing
symptomes at a time of Life when it would be
so difficult to remove them.

I will not add to this already too long letter
by expressing those feelings my present situation
excites but shall only say I am with all the Gra¬
titude his constant kindness claims and all the
esteem Superiour talents commands ever Dr Cullen

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[Page 5]

Dr.
Cullen
Edinburgh

✍
Dunlop of Dunlop.
October 1783
XV. p.1, 3, 31, 84, 219, 306, 425.
volume XVth