Cullen

The Consultation Letters of Dr William Cullen (1710-1790) at the Royal College of Physicians of Edinburgh

 

[ID:3818] From: Dr William Cullen (Professor Cullen) / To: Mr Laurence Edmonston (Edmonstone) / Regarding: Miss Agnes Sanderson (Patient) / 22 May 1776 / (Outgoing)

Reply, 'For Mr Edmonstone's Sister in Law'. Notes her fever but in the main addresses her stomach problems. Appears to be response to letter 1274, but as letter 1634 notes it reached the family after the Sister in Law had died.

Facsimile

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Metadata

FieldData
DOC ID 3818
RCPE Catalogue Number CUL/1/1/7/39
Main Language English
Document Direction Outgoing
Date22 May 1776
Annotation None
TypeScribal copy ( includes Casebook Entry)
Enclosure(s) No enclosure(s)
Autopsy No
Recipe Yes
Regimen No
Letter of Introduction No
Case Note No
Summary Reply, 'For Mr Edmonstone's Sister in Law'. Notes her fever but in the main addresses her stomach problems. Appears to be response to letter 1274, but as letter 1634 notes it reached the family after the Sister in Law had died.
Manuscript Incomplete? No
Evidence of Commercial Posting No

Case

Cases that this document belongs to:

Case ID Description Num Docs
[Case ID:769]
Case of Agnes Sanderson, sister-in-law of Laurence Edmonston suffering from a fever. In a letter dated three years later, Edmonston tells Cullen that she died before the physician's response reached Shetland.
2


People linked to this document

Person IDRole in documentPerson
[PERS ID:1]AuthorDr William Cullen (Professor Cullen)
[PERS ID:605]AddresseeMr Laurence Edmonston (Edmonstone)
[PERS ID:606]PatientMiss Agnes Sanderson
[PERS ID:1]Patient's Physician / Surgeon / ApothecaryDr William Cullen (Professor Cullen)
[PERS ID:605]Patient's Relative / Spouse / FriendMr Laurence Edmonston (Edmonstone)

Places linked to this document

Role in document Specific Place Settlements / Areas Region Country Global Region Confidence
Place of Writing Cullen's House / Mint Close Edinburgh Edinburgh and East Scotland Europe certain
Destination of Letter Buness House Baltasound Shetlands Scotland Europe inferred

Normalized Text

[Page 1]
For Mr Edmonstone's Sister in Law


I'm of your opinions, that I cannot to any useful purpose
say any thing about her fever as it must be over before
you got the answer of. I must therefor suppose her
in the same state as before it. The fever may make
some change of constitution, as I have had spas¬
mod affect
cured by it tho they had subsisted
long before, but cannot say as to your friend.
I in the mean to advise to the first part of
your letter. Dyspepsia depending on a debility
of the whole habit
appearing chiefly in the Stomach,
no reason to consider it as Symptomatic, & while
the Uterine system is so regular, not Hysteric,
except in being affected by passions. Whatever
it be, difficult to cure, as, a disease of the habit
to change that, & to correct congenital debility
confirmed by accident since, & the more difficult
as the mind is weak as the body & is easily affected
by passions. All this an unfavourable Prognosis
sed nil desperandum &c.


We must especially restore or support tone, &
that by Tonic medicines, Exercise, & perhaps
Cold bathing.


As Tonic Medicine, bitters [might be?] useful but you can use
only the bark, & the best form is the cold infusion
ordered below. The Triture is of more consequence than you `
would



[Page 2]

imagine. The vitriolic acid is properly used with
Bark, but give it separately for when joined to the
cold infused, it precipitates the bark. Give
the infusion first, wash it down with a glass of cold
water moderately acidulated with spirit vitriol tenuis.
Proportion the doses according to (↑as↑) the stomach bears
them but never more than for 2 or 3 weeks at a time
You may observe to your friends [&?] that these do not
entirely restrain vomiting but necessary to strengthen
the stomach, & render the vomiting less frequent or [violent?]
& at last remove it altogether If this medicine
do not agree, try the Limatura ferr. præparata.
The formula below. Most stomachs bear larger
doses than was imagined & if she bear easily the
dose here prescribed, increase by degrees till she
can take ℈j for a dose twice a day. The only doubt
to regard to the use of it is her state of menstrua¬
tion, & if the Chalyb. increase it, be more cautious
in its use but the effect of Chalyb. ambigious as
sometimes astringent instead of aperient. Employ
the Chalyb. for a month together & about a fortnight
before the monthly period it is to be begun. Increase
the dose slowly, & lay it aside entirely during the evacua¬
tion & if no effect up on that evacuation be observed;
as soon as it is over, renew the Chalyb., & continue in
as large doses as she easily bears for a fortnight more.


These are the Tonic remedies but they must be long con¬
tinued & other means used before the returns of vomiting
are entirely prevented & in the mean time when vomitings do



[Page 3]

return some other measures are necessary. No ob¬
jections to the Chamomile tea for washing out the
brown bile disturbing the stomach, but never go far
in thus encouraging vomiting but after washing out
the stomach a little, stop the vomiting by an Opiate.


I agree with you the habitual use of Opiates [might?] do
much harm to the stomach but this must not hinder us
to employ them to the degree that is necessary to remove
Spasmodic affectations, therefore I would employ them
both to check the violent vomitings [when?] come on, & prevent
their returns [when?] can be foreseen. This difficult in a
case as this of daily vomiting but in such I have
succeeded by ye Stomachic drops ordered below, about
an hour before dinner. If the Elixir render the
medicine very disagreeable, lay it aside & give the
Laudan. alone. increasing it as necessary & [born?] &
the trial this way [might be?] farther, & oftener, or seldomer
as your discretion shall direct. In a violent fit
of vomiting & the Laudan. given by the mouth be
rejected, then give it by glyster & in the dose
necessary.


Obviate costiven. One of the best Laxat. for her is
Magnesia, but this must not be employed so often
when taking the Chalybeate, & in place of it give
an Aloetic pill.


Exercise Riding when strength & weather allow
& even sailing but let it be something of a voyage




[Page 4]


Cold bathing attempting it attend to two things
1. breast be sound, free from cough or suspicion
of obstruction
2. be taken [when?] indoors, bringing on the cold gradually
i.e. by employing first one part boiling water to three
parts spring or sea water & afterwards gradually diminishing the proportion of the boiling water & c.


Her Diet must depend up on her particular ex¬
perience than by any general rules I can give
but tho solid let it be light, & always little at
one time allowing that to be compensated by the fre¬
quency.


Neither a putrid nor an inflammatory diathesis to
be suspected, & the disease is to be considered as an
affection of the [mocs?] powers.

For

Take half an ounce of Powdered Peruvian bark, In mortar vitriol viride [marimor.?] with a little spring water as semiliquid to be blended carefully [& hor.?] then add up to two pounds of spring water [Reponatr?] in [a lagena?] & macerate for seven hours, then add four ounces of a Tincture of simple Peruvian bark and after it has settled, strain. Label: Stomachic Infusion an ounce or 2, 2 or 3 times a day, to be washed down with et cetera.

Take prepare three grains of steel, six grains powdered Cinnamon, ten grains of white sugar, Mix to make [Pills?] and make in this way twelve doses Label: Stomachic powders one, twice a day in Currant jelly.

Take one drachm Elixir proprietatis and two ounces Liquid Laudanum Label: Stomachic drops from 50 to 100 for a dose & on a bit of sugar

22 May 1776
W.C.

Diplomatic Text

[Page 1]
For Mr Edmonstone's Sister in Law


I'm of your opinions, yt I cannot to any useful purpose
say any yg abt her fever as it must be over before
you got ye answer of. I must theref suppose her
in ye same state as before it. The fever may make
some change of constitution, as I have had spas¬
mod affect
cured by it tho they had subsisted
long before, but cannot say as to your friend.
I in the mean to advise to the first part of
your letter. Dyspepsia dependg on a debility
of ye whole habit
appearg chiefly in ye Stom.,
no reason to consider it as Symptomatic, & while
the Uterine system is so regular, not Hysteric,
except in being affected by passions. Whatever
it be, difficult to cure, as, a disease of the habit
to change that, & to correct congenital debility
confirmed by accident since, & the more diffict
as ye mind is weak as ye body & is easily affected
by passions. All this an unfavourable Progn.
sed nil desperandum &c.


We must especially restore or support tone, &
that by Tonic medicines, Exercise, & perhaps
Cold bathing.


As Ton. Med., bitters [m.b.?] useful but you can use
only ye bark, & ye best form is ye cold infusion
ordd below. The Triture is of more conseq. yn you `
would



[Page 2]

imagine. The vitriolic acid is properly used w
Bark, but give it separately for wn joined to the
cold infused, it precipitates the bark. Give
ye infusion first, wash it down w a glass of cold
water moderately acidulated w Spt vitr tenuis.
Proportion the doses accordg to (↑as↑) the stomach bears
them but never more yn for 2 or 3 weeks at a time
You may observe to your friends [&?] yt these do not
entirely restrain vomitg but necessary to strengthen
ye stomach, & render ye vomitg less freqt or [violent?]
& at last remove it altogether If this medicine
do not agree, try the Limatura ferr. præparata.
The formula below. Most stomachs bear larger
doses than was imagined & if she bear easily the
dose here prescribed, increase by degrees till she
can take ℈j for a dose twice a day. The only doubt
to regard to the use of it is her state of menstrua¬
tion, & if ye Chalyb. increase it, be more cautious
in its use but the effect of Chalyb. ambigious as
sometimes astringent instead of aperient. Employ
the Chalyb. for a month together & about a fortnt
before the monthly period it is to be begun. Increase
ye dose slowly, & lay it aside entirely durg ye evacua¬
tion & if no effect up on that evacuatn be observed;
as soon as it is over, renew ye Chalyb., & continue in
as large doses as she easily bears for a fortnt more.


These are ye Tonic remed. but they must be long con¬
tinued & other means used before ye returns of vomitg.
are entirely prevented & in ye mean time wn vomitgs do



[Page 3]

return some other measures are necessary. No ob¬
jections to the Chamomile tea for washg out ye
brown bile disturbg ye stomach, but never go far
in thus encouraging vomitg. but after washg out
ye Stom. a little, stop ye vomitg. by an Opiate.


I agree w you ye habitual use of Opiates [m?] do
mc harm to ye Stom. but this must not hinder us
to employ ym to ye degree yt is necessary to remove
Spasmodic affectations, therefore I would employ them
both to check ye violt vomitgs [wn?] come on, & prevent
their returns [wn?] can be foreseen. This difficult in a
case as this of daily vomitg. but in such I have
succeeded by ye Stomachic drops ordd below, about
an hour before dinner. If ye Elixir render ye
medicine very disagreeable, lay it aside & give ye
Laudan. alone. increasg it as necessary & [born?] &
the trial this way [m. b.?] farther, & oftener, or seldomer
as your discretion shall direct. In a violent fit
of vomitg & ye Laudan. given by ye mouth be
rejected, then give it by glyster & in the dose
necessary.


Obviate costiven. One of ye best Laxat. for her is
Magnesia, but this must not be employed so often
wn taking ye Chalybeate, & in place of it give
an Aloetic pill.


Exercise Ridg wn strength & weather allow
& even sailg but let it be somethg of a voyage




[Page 4]


Colbathg attemptg it attend to two things
1. breast be sound, free from cough or suspicion
of obstruction
2. be taken [w?] indoors, bringg on ye cold gradually
i.e. by employing first one pt boilg wat to three
pts spring or sea water & afterwds gradually dimi¬
nishg ye proportion of ye boilg. water & c.


Her Diet must depend up on her particular ex¬
perience than by any general rules I can give
but tho solid let it be light, & always little at
one time allowg yt to be compensated by the fre¬
quency.


Neither a putrid nor an inflammatory diathesis to
be suspected, & ye disease is to be considered as an
affection of ye [mocs?] powers.

For


℞ Pulv. cort. Peruv. ℥ſs In mortar vitr. v. [marimor.?]
cum Aq. f pauxilla ut semiliquid fiat lento diligenter
[& hor.?] dein adde Aq. f. ad lbij [Reponatr?] in lagena
& macera h. xii d. adde Tinct. c Peruv. simpl. ℥iv
& post subsident cola S. Stomachic Infus. an ounce
or 2, 2 or 3 times a day, to be washed down w & c


Limat m. pptt gr. iij Cinnam. pulv. gr. vj
Sacch. alb. duriss gr. x ℳ f. P. et f. h. m. dos № XII
S. Stomachic powders one, 2ce a day in Currant jelly.
N.B. The Infus. & Powders not to be used at ye same time.


Elix. propriet. ℥i Laud. liquid. ʒij S. Stomachic
drops from 50 to 100 for a dose & on a bit of sugar

22 May 1776
W.C.

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