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A young Lady 23 years old, of a fair and freckled com¬
plexion, with brown hair, about six weeks ago incautiously
exposed herself during the Catamenia to cold. This occasioned
a sudden cessation of the flux, and was followed in the
course of a few hours, by violent agitation of the whole
frame, with a most laborious dyspnœa, coldness of the
extremities, and a rigid contraction of the muscles of the
thumb and fingers, which continued for more than an
hour. Her pulse all this time was quick and feeble; and
her senses unaffected. These symptoms have recurred
frequently, once, twice, or thrice, in 24 hours, with different
degrees of violence; but seldom with so much as in the
first attack, upon the first approach of the ↑Late↑ menstrual period,
(which was about 10 days since) she experienced a more
frequent visitation of her disorder. The Flux continued
for somewhat more than 2 days, in the usual quantity, and
then suddenly ceased, but with little or no aggravation of
her disease. She is previous to the attack of Dyspnœa,
with a rigidity of the hands, (of which the muscles of the
neck and throat; seem now to partake in a small degree)
sensible of a sinking, or uneasy sensation, at the scrobiculous
cordis, and upon the paroxysm ceasing, is extreamly languid

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and faint, the lightest fluids producing, a sense of weight
and fullness in the stomach. She is often teazed with sickness
and fruitless efforts to vomit; which continue for many hours
her bowels are generally loose, she has constantly 2 or 3
stools, either spontaneously or by the aid of medicine in
24 hours. Indeed in the best state of health she has an
intestinal evacuation daily to this amount. In the
absence of these troubling symptoms, she feels herself
easy, converses with her friends chearfully, and excepting
a hoarseness, appears to an indifferent spectator, not ill.
She is become thinner, and is reduced much in her strength.
She is at all times a very little eater, but since the attack
of her present disorder, has a general dislike to all kinds
of food; but the mildest and most insipid, are the least offensive
to her. She is very uncertain as to sleep, frequently passes
the night without any, notwithstanding the use of Opium,
and often after many hours rest, wakes unrefreshed, and
is unexpectedly visited by a return of her disorder. Any
sudden impression made upon the sense of hearing, or anxiety
of mind, has immediately brought on the disease; and the
latter she has been most unfortunately subject to, for many
months, having been employed in the tender offices of an
affectionate and dutiful child, to a most amiable sister and
parent. There is little or no increase of heat at any time,

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in the frame; her tongue preserves its cleanness entirely
tho' she frequently complains much of thirst, but is very
often prevented gratifying it, from the weight & uneasiness,
fluids are apt to occasion in the stomach. For these
complaints, Emetics have repeatedly been given. The state
of the stomach and bowels, has been specially attended to;
and a daily evacuation has been procured, when there has
been any tardiness, by Aloetic purgatives, by Rhubarb,
by senna, and by Castor Oil, in such quantity and manner
as seemed proper. Strong solutions of Assafœtida, with
volatile salt, and Laudanum, have been often administred.
Camphor in substance, and solution, has been very frequently
taken with some advantage. Other fœtids have been also
employed, different preparations of Amber, Essential Oils,
Musk, Ol Animale, and Balsam of Peru, have in their
turns been taken, occasionally combined with Volatile salt
and Opium, {illeg}. The Pediluvium
and warm bath, ↑with↑ Blisters have been ↑also↑ been repeatedly applied.
In the absence of the paroxysm, a powerful tonic treatment
has been used, and bark and steel have been given with
freedom, neither have embrocations to the stomach, and
spine of the back, been neglected. From these various means
some advantage, has been at times gained, but nothing
permanent. A total absence of her uneasy symptoms

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with perfect tranquility in the frame, has been waited for,
under a wish to employ the Cold Bath. Do small but
repeated ↑Electrical↑ shocks promise anything in this formidable
complaint? A milk diet has been recommended with
Vegetables. Will the Cicuta be of use here? The mineral (↑metalline↑)
Antispasmodics, as the flores Zinci, & Cuprum Ammoniacum
are at present proposed to be tried for in some days. -----